What can Glow in the dark Contact Lenses do?

Glow in the dark technology has been widely used in safety project and decoration, But with the development of technology, glow in the dark pigment usage has been more widely Beyond your imagination such Treatment of eye diseases. California Institute of Technology grad student Colin Cook proposed a new way to treat diabetes-related eye diseases in a less-painful and less-invasive way than current treatments. Glow in the dark contact lenses.

Millions of people around the world suffer from diabetes, and eye disease can be one of the most dangerous and painful effects of diabetes. According to the National Institute of Ophthalmology, all forms of diabetic eye disease – from glaucoma to diabetic retinopathy – can cause severe vision loss or blindness. An engineering student wants to change these possibilities.

California Institute of Technology grad student Colin Cook proposed a new way to treat diabetes-related eye diseases in a less-painful and less-invasive way than current treatments. Cook worked alongside other researchers from Caltech’s electrical and medical engineering teams to create a unique solution: glow in the dark contact lenses.

Most diabetic eye problems arise from diseases that damage the entire body’s blood vessels, but have a significant effect on people in the eye. Changes in blood flow to nerve cells cause those cells to die in the retina. The disease continues to stop the flow of blood and the infected person continues to lose sight. The body naturally resists this problem. However, people with diabetes tend to develop poor vessels trying to replace dying vessels. Weakened blood vessels often flow out of the clear liquid in the eye.

Cook noted that the problems largely stem from an insufficient supply of oxygen to the vessels. Thus, he theorized that there could be a new way to reduce the retina’s oxygen demands. (Previously, it involved taking lasers to someone’s eyeball in order to burn away cells along the outer part of the retina.)

Cook’s contact lenses are significantly less intrusive than the lasers, has fewer side effects, and do the same thing. The lenses reduce the metabolic demands on the retina by monitoring the eye’s rod cells. Rod cells help humans see in low-light conditions. They use up considerably more oxygen in dark spaces rather than outside in the sunlight.

“Your rod cells, as it turns out, consume about twice as much oxygen in the dark as they do in the light,” Cook said.

Cook designed the lenses to reduce what the retina needs for it night-time functions by giving rod cells a very faint light to look at while the wearer is asleep.

“If we turn metabolism in the retina down, we should be able to prevent some of the damage that occurs,” he said.

The illumination on the lense happens thanks to tiny vials of tritium. This radioactive version of hydrogen sends out electroncs while it decays. Those electrons get transformed into light by a phosphorescent coating, guaranteeing that there will always be light throughout the lifetime of a single contact lens.

There’s a growing trend toward light therapy both for the general public and also for sufferers of diabetic retinopathy. Light therapy sleep masks had been a unique and non-invasive option for years. However, the mask would often slip off, causing incoming light to distract a wearer.

Cook said his lenses place the light source directly on the eye and everything moves together.

“There’s neural adaptation that happens when you have a constant source of illumination on the eye. The brain subtracts that signal from the vision and the wearer will perceive dark again in just a few seconds,” he said.

According to Cook and his team, the retinas get appropriate light thanks to a strategic lens design.

“As we sleep, our eyes roll back. For a sleep mask this means the eye is no longer receiving as much light, but glow in the dark contact lenses move with the eye, so there is no such problem,” he noted.

Currently, Cooke said that he and other researchers will test the lens to achieve true preventive measures. To test his project, Cooke hopes to get FDA permission to conduct clinical trials. The project also won the top medical technology of Princeton University’s entrepreneurial competition TigerLaunch.

Cook said: “It’s very exciting to get our work recognized by a team of venture capitalists, but then it comes out and shares stories about relatives affected by the disease. These stories really made my efforts revive. .”